Sensation Seeking in Long-Term Abstinent Alcoholics, Treatment-Naïve Active Alcoholics, and Nonalcoholic Controls
نویسندگان
چکیده
منابع مشابه
Increased white matter signal hyperintensities in long-term abstinent alcoholics compared with nonalcoholic controls.
BACKGROUND The harmful effects of alcohol dependence on brain structure and function have been well documented, with many resolving with sufficient abstinence. White matter signal hyperintensities (WMSH) are thought to most likely be consequences secondary to the vascular (i.e., hypertension and atherosclerosis) effects of AD. We hypothesized that such effects would persist into long-term absti...
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In order to establish whether long-term abstinence from alcohol reverses the defective serotonergic and GABAergic controls of growth hormone (GH) secretion affecting alcoholic patients, the 5-HT1D serotonergic receptor agonist sumatriptan and the GABAergic agent gamma-hydroxybutyric acid (GHB) were administered to 12 normal men (32-49 years) and 22 non-depressed male alcoholic subjects (38-52 y...
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ژورنال
عنوان ژورنال: Alcoholism: Clinical and Experimental Research
سال: 2010
ISSN: 0145-6008,1530-0277
DOI: 10.1111/j.1530-0277.2010.01179.x